HAART Chart - Approved Antiretroviral Drugs

Generic (Common) Name

Brand Name

Company

Year Approved

Protease Inhibitors (PIs)

amprenavir

Agenerase

GlaxoSmithKline

1999;
withdrawn 2007

atazanavir

Reyataz

Bristol-Myers Squibb

2003

darunavir (TMC114)

Prezista

Tibotec

2006

fosamprenavir

Lexiva (U.S.); Telzir (Europe)

GlaxoSmithKline

2003

indinavir

Crixivan

Merck

1996

lopinavir/ritonavir

Kaletra

Abbott

2000; Meltrex formulation 2005

nelfinavir

Viracept

Pfizer

1997

ritonavir

Norvir

Abbott

1996

saquinavir

Invirase (hard gel)
Fortovase (soft gel)

Roche

1995
1997; withdrawn 2005

tipranavir

Aptivus

Boehringer Ingelheim

2005

Nucleoside/Nucleotide Reverse Transcriptase Inhibitors (NRTIs)

abacavir

Ziagen

GlaxoSmithKline

1998

didanosine (ddI)

Videx

Bristol-Myers Squibb

1989; Videx EC 2000

emtricitabine (FTC)

Emtriva

Gilead

2003

lamivudine (3TC)

Epivir

GlaxoSmithKline

1995

stavudine (d4T)

Zerit

Bristol-Myers Squibb

1994

tenofovir DF

Viread

Gilead

2002

zalcitabine (ddC)

Hivid

Roche

1992; withdrawn 2005

zidovudine (AZT)

Retrovir

GlaxoSmithKline

1987

Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)

delavirdine

Rescriptor

Pfizer

1997

efavirenz

Sustiva (U.S.); Stocrin (elsewhere)

Bristol-Myers Squibb

1998

Etravirine

Intelence

Tibotec

2008

nevirapine

Viramune

Boehringer Ingelheim

1996

Other Classes

enfuvirtide (T-20; fusion inhibitor)

Fuzeon

Trimeris

2003

maraviroc (CCR5 antagonist)

Selzentry (U.S.);

Celsentri (elsewhere)

Pfizer

2007

raltegravir (integrase inhibitor)

Isentress

Merck

2007

Fixed-Dose Combinations

lamivudine/abacavir (NRTI)

Epzicom (U.S.); Kivexa (Europe)

GlaxoSmithKline

2004

tenofovir/emtricitabine (NRTI)

Truvada

Gilead

2004

tenofovir/emtricitabine/
efavirenz (NRTI/NNRTI)

Atripla

Gilead/Bristol-Myers Squibb

2006

zidovudine/lamivudine (NRTI)

Combivir

GlaxoSmithKline

1997

zidovudine/lamivudine/abacavir (NRTI)

Trizivir

GlaxoSmithKline

2000